Assessments Conducted on TSCA Work Plan Chemicals Prior to June 22, 2016

Prior to the Toxic Substances Control Act (TSCA) amendments on June 22, 2016, EPA had conducted a number of assessments on TSCA Work Plan Chemicals. The status of those assessments are provided below.

Learn more about EPA’s current risk evaluations for chemicals under amended TSCA

Completed Risk Assessments

• Antimony Trioxide (ATO): This risk assessment addresses effects on ecological receptors from the use of antimony trioxide (ATO) as a synergist in halogenated flame retardants. On August 28, 2014, EPA released the final risk assessment that indicated no concern for this use of ATO.
  • CASRN: 1309-64-4
  • Initiated: 2012
  • Completed: 2014
  • Peer Review Plan
  • Draft Assessment and Public Comments (Docket: EPA-HQ-OPPT-2012-0724)
  • Peer Review Site
  • Peer Review Report
  • Final Risk Assessment
  • Response to Comments

• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8,-hexamethylcyclopenta[γ]-2-benzopyran (HHCB): This risk assessment addresses ecological risks from HHCB as a fragrance ingredient in commercial and consumer products. On August 28, 2014, EPA released the final risk assessment that indicated no concern for this use of HHCB.
  • CASRN: 1222-05-5
  • Initatied: 2012
  • Completed: 2014
  • Peer Review Plan
  • Draft Assessment and Public Comments (Docket: EPA-HQ-OPPT-2012-0722)
  • Peer Review Site
  • Peer Review Report
  • Final Risk Assessment
  • Response to Comments

Completed Problem Formulation and Initial Assessments

• Brominated Phthalate Cluster: On August 13, 2015, EPA released a data needs assessment for the Brominated Phthalate Cluster used as flame retardants in polyurethane foams.  During problem formulation, EPA/OPPT reviewed previous assessments and identified critical gaps in toxicity, exposure, and commercial mixtures data. The data needs assessment is intended to guide the collection of additional data and information. Chemical in bold is on EPA’s 2014 TSCA Work Plan.
  • Cluster chemicals
    • 1,2-Benzenedicarboxylic acid, 3,4,5,6-tetrabromo-, 1,2-bis(2-ethylhexyl) esters (TBPH, CASRN: 26040-51-7)
    • Benzoic acid, 2,3,4,5-tetrabromo-, 2-ethylhexyl esters (TBB, CASRN: 183658-27-7)
    • 2-(2-Hydroxyethoxy)ethyl 2-hydroxypropyl 3,4,5,6-tetrabromobenzenedicaroxylate (CASRN: 77098-07-8)
    • 3,4,5,6-Tetrabromo-1,2-benzenedicarboxylic acid, mixed esters with diethylene glycol and propylene glycol (CASRN: 20566-35-2)
    • 1,2- (2,3-dibromopropyl) benzenedicarboxylate (CASRN: 7415-86-3)
  • Two substances in the Brominated Phthalates Cluster Flame Retardants Workplan were identified as Confidential A and Confidential B.  Please be advised that these two substances refer to chemicals reported in the TSCA section 5 program as P-96-0965 and P-04-0404.
  • Initiated: 2013
  • Data Needs Assessment (EPA–HQ–OPPT– 2014-0491)
  • BPC Data Needs Assessment Technical Supplement: P Chem and Fate
  • BPC Data Needs Assessment Technical Supplement: Use and Exposure
  • BPC Data Needs Assessment Technical Supplement: Hazard
  • Fact Sheet on flame retardant clusters

• Chlorinated Phosphate Esters Cluster: On August 13, 2015, EPA released a problem formulation for Chlorinated Phosphate Esters used as flame retardants in furniture foams and textiles. The goal of this problem formulation was to identify scenarios where further risk analysis may be necessary. The conclusion of this problem formulation is that EPA will assess risks to consumers, the general population and aquatic organisms exposed as a result of manufacture, processing and use of chlorinated phosphate esters cluster members. Chemical in bold is on EPA’s 2014 TSCA Work Plan
  • Cluster chemicals
    • Ethanol, 2-chloro-, phosphate (3:1) (TCEP, CASRN: 115-96-8)
    • 2-Propanol, 1-chloro-, 2,2’,2’’-phosphate (TCPP, CASRN: 13674-84-5)
    • 2-Propanol, 1,3-dichloro-, phosphate (3:1) (TDCPP, CASRN: 13674-87-8)
  • Initiated: 2014
  • Problem Formulation and Initial Assessment (Docket: EPA-HQ-OPPT-2015-0068)
  • Fact Sheet on flame retardant clusters

• Tetrabromobisphenol A and Related Chemicals Cluster: On August 13, 2015, EPA released a problem formulation for TBBPA and related chemicals used as a flame retardants in plastics/printed circuit boards for electronics. The goal of this problem formulation was to identify scenarios where further risk analysis may be necessary. The conclusion of this problem formulation is that EPA will assess risks to workers, consumers, the general population and aquatic, sediment- and soil-dwelling organisms exposed due to the manufacture, processing and use of TBBPA. Chemical in bold is on EPA’s 2014 TSCA Work Plan
  • Cluster chemicals
    • Tetrabromobisphenol A (TBBPA, CASRN: 79-94-7)
    • TBBPA-bis(dibromopropyl ether) (CASRN: 21850-44-2)
    • TBBPA-bis(ally ether) (CASRN: 25327-89-3)
    • TBBPA-bis(methyl ether) (CASRN: 37853-61-5)
  • Initiated: 2014
  • Problem Formulation and Initial Assessment (Docket: EPA-HQ-OPPT-2014-0730)
  • Supplemental File 1 TBBPA Biomonitoring
  • Supplemental File 2 TBBPA Environmental Monitoring
  • Supplemental File 3 TBBPA Residential Monitoring
  • Supplemental File 4 Cancer Assessment Review Committee Report
  • Fact Sheet on flame retardant clusters